Six-month outcomes in a multinational Registry of patients hospitalized with an Acute Coronary syndrome (the Global Registry of Acute Coronary Events [GRACE])
Identifieur interne : 00AA88 ( Main/Exploration ); précédent : 00AA87; suivant : 00AA89Six-month outcomes in a multinational Registry of patients hospitalized with an Acute Coronary syndrome (the Global Registry of Acute Coronary Events [GRACE])
Auteurs : Robert J. Goldberg [États-Unis, Australie, France, Canada, Royaume-Uni] ; Kristen Currie ; Kami White ; David Brieger ; Phillippe Gabriel Steg ; Shaun G. Goodman ; Omar Dabbous ; Keith A. A. Fox ; Joel M. GoreSource :
- The American journal of cardiology [ 0002-9149 ] ; 2004.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
Relatively limited data are available, particularly from the perspective of a multinational registry, about the post-discharge outcomes and management practices of patients with an acute coronary syndrome (ACS). The objectives of this longitudinal study were to examine 6-month outcomes in a large multinational sample of patients hospitalized with an ACS. A total of 5,476 patients with ST-segment elevation acute myocardial infarction (STEAMI), 5,209 patients with non-ST-segment elevation acute myocardial infarction (NSTEAMI), and 6,149 patients with unstable angina pectoris discharged from 90 hospitals in 14 countries comprised the study population. The study sample was recruited from 18 cluster sites in 14 countries that are currently collaborating in the Global Registry of Acute Coronary Events (GRACE) study. The 6-month post-discharge death rates were 4.8% in patients with STEAMI, 6.2% in patients with NSTEAMI, and 3.6% in patients with unstable angina pectoris. Approximately 1 in 5 of each of our comparison groups were rehospitalized for heart disease during the 6-month follow-up, and approximately 15% of each of the respective study cohorts underwent coronary revascularization during follow-up. Demographic and clinical characteristics of post-discharge decedents were identified according to type of ACS. Our results suggest that a considerable proportion of patients who were discharged from the hospital after an ACS, with some differences noted according to type of ACS, remain at increased risk for adverse outcomes during the relatively brief post-discharge period. These data suggest the need for better long-term medical management and more intense follow-up of patients with an ACS to improve their long-term outlook.
Affiliations:
- Australie, Canada, France, Royaume-Uni, États-Unis
- Massachusetts, Nouvelle-Galles du Sud, Ontario, Écosse, Île-de-France
- Paris, Sydney, Toronto, Édimbourg
- Université de Toronto
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Le document en format XML
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Goldberg</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Medicine, Division of Cardiovascular Medicine and Center for Outcomes Research, University of Massachusetts Medical School</s1><s2>Worcester, Massachusetts</s2><s3>USA</s3></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Concord Hospital</s1><s2>Sydney</s2><s3>AUS</s3></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Service de Cardiologie, Hôpital Bichat</s1><s2>Paris</s2><s3>FRA</s3></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="04"><s1>Canadian Heart Research Centre and Terrence Donnelly Heart Center, Division of Cardiology, St. Michael's Hospital, University of Toronto</s1><s2>Toronto, Ontario</s2><s3>CAN</s3></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Department of Cardiology, The University and the Royal Infirmary of Edinburgh</s1><s2>Edinburgh</s2><s3>GBR</s3></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Currie, Kristen" sort="Currie, Kristen" uniqKey="Currie K" first="Kristen" last="Currie">Kristen Currie</name></author><author><name sortKey="White, Kami" sort="White, Kami" uniqKey="White K" first="Kami" last="White">Kami White</name></author><author><name sortKey="Brieger, David" sort="Brieger, David" uniqKey="Brieger D" first="David" last="Brieger">David Brieger</name></author><author><name sortKey="Steg, Phillippe Gabriel" sort="Steg, Phillippe Gabriel" uniqKey="Steg P" first="Phillippe Gabriel" last="Steg">Phillippe Gabriel Steg</name></author><author><name sortKey="Goodman, Shaun G" sort="Goodman, Shaun G" uniqKey="Goodman S" first="Shaun G." last="Goodman">Shaun G. 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Gore</name></author></analytic><series><title level="j" type="main">The American journal of cardiology</title><title level="j" type="abbreviated">Am. j. cardiol.</title><idno type="ISSN">0002-9149</idno><imprint><date when="2004">2004</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">The American journal of cardiology</title><title level="j" type="abbreviated">Am. j. cardiol.</title><idno type="ISSN">0002-9149</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute</term><term>Coronary artery</term><term>Coronary heart disease</term><term>Evolution</term><term>Human</term><term>Prognosis</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Cardiopathie coronaire</term><term>Pronostic</term><term>Evolution</term><term>Homme</term><term>Aigu</term><term>Artère coronaire</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Relatively limited data are available, particularly from the perspective of a multinational registry, about the post-discharge outcomes and management practices of patients with an acute coronary syndrome (ACS). The objectives of this longitudinal study were to examine 6-month outcomes in a large multinational sample of patients hospitalized with an ACS. A total of 5,476 patients with ST-segment elevation acute myocardial infarction (STEAMI), 5,209 patients with non-ST-segment elevation acute myocardial infarction (NSTEAMI), and 6,149 patients with unstable angina pectoris discharged from 90 hospitals in 14 countries comprised the study population. The study sample was recruited from 18 cluster sites in 14 countries that are currently collaborating in the Global Registry of Acute Coronary Events (GRACE) study. The 6-month post-discharge death rates were 4.8% in patients with STEAMI, 6.2% in patients with NSTEAMI, and 3.6% in patients with unstable angina pectoris. Approximately 1 in 5 of each of our comparison groups were rehospitalized for heart disease during the 6-month follow-up, and approximately 15% of each of the respective study cohorts underwent coronary revascularization during follow-up. Demographic and clinical characteristics of post-discharge decedents were identified according to type of ACS. Our results suggest that a considerable proportion of patients who were discharged from the hospital after an ACS, with some differences noted according to type of ACS, remain at increased risk for adverse outcomes during the relatively brief post-discharge period. These data suggest the need for better long-term medical management and more intense follow-up of patients with an ACS to improve their long-term outlook.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Canada</li><li>France</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Massachusetts</li><li>Nouvelle-Galles du Sud</li><li>Ontario</li><li>Écosse</li><li>Île-de-France</li></region><settlement><li>Paris</li><li>Sydney</li><li>Toronto</li><li>Édimbourg</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><noCountry><name sortKey="Brieger, David" sort="Brieger, David" uniqKey="Brieger D" first="David" last="Brieger">David Brieger</name><name sortKey="Currie, Kristen" sort="Currie, Kristen" uniqKey="Currie K" first="Kristen" last="Currie">Kristen Currie</name><name sortKey="Dabbous, Omar" sort="Dabbous, Omar" uniqKey="Dabbous O" first="Omar" last="Dabbous">Omar Dabbous</name><name sortKey="Fox, Keith A A" sort="Fox, Keith A A" uniqKey="Fox K" first="Keith A. A." last="Fox">Keith A. A. Fox</name><name sortKey="Goodman, Shaun G" sort="Goodman, Shaun G" uniqKey="Goodman S" first="Shaun G." last="Goodman">Shaun G. Goodman</name><name sortKey="Gore, Joel M" sort="Gore, Joel M" uniqKey="Gore J" first="Joel M." last="Gore">Joel M. Gore</name><name sortKey="Steg, Phillippe Gabriel" sort="Steg, Phillippe Gabriel" uniqKey="Steg P" first="Phillippe Gabriel" last="Steg">Phillippe Gabriel Steg</name><name sortKey="White, Kami" sort="White, Kami" uniqKey="White K" first="Kami" last="White">Kami White</name></noCountry><country name="États-Unis"><region name="Massachusetts"><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></region></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></region></country><country name="France"><region name="Île-de-France"><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></region></country><country name="Canada"><region name="Ontario"><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></region></country><country name="Royaume-Uni"><region name="Écosse"><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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